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Mark L Chapman Selected Research

5- (4- butoxy- 3- chlorophenyl)- N- ((2- morpholinopyridin- 3- yl)methyl)nicotinamide

9/2010A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats.

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Mark L Chapman Research Topics

Disease

5Pain (Aches)
11/2016 - 02/2008
5Neuralgia (Stump Neuralgia)
05/2015 - 02/2008
2Chronic Pain
05/2015 - 02/2008
1Seizures (Absence Seizure)
04/2021
1Hyperalgesia
09/2010
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
04/2004
1Spontaneous Abortion (Miscarriage)
04/2004
1Congenital Abnormalities (Deformity)
04/2004
1Premature Birth (Birth, Premature)
04/2004
1Ectopic Pregnancy
04/2004

Drug/Important Bio-Agent (IBA)

5Sodium Channels (Sodium Channel)IBA
11/2016 - 02/2008
2Voltage-Gated Sodium ChannelsIBA
01/2016 - 02/2008
2Biological ProductsIBA
11/2010 - 02/2008
2Analgesics (Analgesic Drugs)IBA
11/2010 - 02/2008
2Sodium Channel BlockersIBA
09/2010 - 06/2008
1OxadiazolesIBA
04/2021
16- amino- 5- (2,3,5- trichlorophenyl)pyridine- 2- carboxylic acid methylamideIBA
05/2015
1Ion Channels (Ion Channel)IBA
05/2015
1Pharmaceutical PreparationsIBA
08/2014
1PyrazinesIBA
11/2010
15- (4- butoxy- 3- chlorophenyl)- N- ((2- morpholinopyridin- 3- yl)methyl)nicotinamideIBA
09/2010
1Lamotrigine (Lamictal)FDA LinkGeneric
06/2008
1furanIBA
06/2008
1Mexiletine (Mexitil)FDA LinkGeneric
06/2008
1PiperazineIBA
06/2008
1Antisense OligonucleotidesIBA
02/2008
1Tetrodotoxin (Tetradotoxin)IBA
02/2008
1Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric
04/2004
1Cyclosporine (Ciclosporin)FDA LinkGeneric
04/2004
1Metronidazole (Metric)FDA LinkGeneric
04/2004
1Prednisone (Sone)FDA LinkGeneric
04/2004
1Ciprofloxacin (Cipro)FDA LinkGeneric
04/2004
1Azathioprine (Imuran)FDA LinkGeneric
04/2004

Therapy/Procedure

2Therapeutics
11/2016 - 08/2014
2Oral Administration
11/2010 - 09/2010
1Analgesia
02/2008
1Therapeutic Abortion
04/2004